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Men who have taken esomeprazole have said the same thing: more than half of those who take it have suffered heart attacks and strokes.
A study published Tuesday in the journalJAMA Network Opensuggests that those who take the drug for heart disease may suffer some form of gastrointestinal side-effects.
The study, which was led by researchers from the University of Cincinnati and the University of Florida, compared the heart health of participants taking a combination of esomeprazole (the active ingredient in Nexium) and omeprazole (the ingredient in Prilosec). Both drugs have been shown to have a similar effect, but the results were inconsistent.
Esomeprazole and omeprazole are often prescribed to treat conditions such as gastroesophageal reflux disease and peptic ulcers, respectively.
But the researchers said the results were interesting enough to suggest that people taking the drugs may suffer some form of gastrointestinal side-effects, and may need to avoid the drugs altogether.
“This is an interesting finding that is important because it shows that even though people who take omeprazole and esomeprazole may suffer gastrointestinal side-effects, they do have a slightly lower incidence of these effects,” said study co-leader David Goldfarb, MD, a professor of surgery at the University of Miami and a co-author of the study.
Dr. Goldfarb said he had hoped that the findings would help to raise awareness about the potential side-effects of drugs.
“We need to make sure that people who are taking them are aware that they are also taking other drugs that may interact with omeprazole and esomeprazole,” he said.
The drug omeprazole may also interact with other drugs, such as rilpivirine, a prescription medicine used to treat COVID-19, the study authors said.
Researchers at University of Florida and Mayo Clinic said they did not see any difference in heart rates between the two drugs.
Goldfarb said he hoped the findings would help to raise awareness about the potential side-effects of drugs.
Goldfarb said he expected the findings to help raise awareness about the potential side-effects of drugs.
“The idea that we are seeing a benefit to people taking drugs that have similar effects on the gastrointestinal tract, but may interact with other drugs is not right,” he said.
The study, which was led by researchers from the University of Cincinnati and the University of Florida, was published in theJournal of the American Medical Associationon Tuesday.
Goldfarb said the results were interesting enough to suggest that people who are taking the drugs may suffer some form of gastrointestinal side-effects, and may need to avoid the drugs altogether.
“This is an interesting finding that is important because it shows that even though people who take the drugs may suffer from some form of gastrointestinal side-effects, they do have a slightly lower incidence of these effects,” he said.
Goldfarb said he expected the findings to help to raise awareness about the potential side-effects of drugs.
Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
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Copyright(c) 2021 PinnICreative, Inc.
This document is designed for educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease or health condition. Any advice or medical advice must be reviewed by the doctor the advice of the provider. PinnICreative, Inc. encourages all online resource suggestions and encourages all people to consider us as their online resource.All trademarks and registered trademarks are the property of their respective owners. Inbox<pcontains this material: | Add some extra information if required | Includes link to original productIt is not intended to diagnose, treat, cure, or prevent any disease or health problem. Any advice or medical advice must be reviewed by the doctor the advice of the provider of the advice of the specialist.Nexium is a brand-name prescription drug manufactured and time-release tablets for your treatment needs. Nexium 20mg is used in adults to help reduce the chances of heart disease and other related problems due to either cancer or heart disease. It is used to treat either frequent heartburn or a smaller, more frequent type of heartburn known as heartburn in adults. Nexium 20mg can also be used to treat smaller, more frequent frequent heartburn (occurs 2 or more days a week). Nexium 20mg is used to treat adults for frequent or slow heartburn. It is used to treat adults for frequent heartburn (occurs 2 or more days a week) as well as heartburn in adults.
Nexium belongs to a class of drugs known as proton pump inhibitors. It belongs to a class of drugs known as proton pump inhibitors also known as “Heparin”.
Nexium is a proton pump inhibitor. It works by blocking the enzyme which produces the acid in your stomach when you have frequent heartburn. This enzyme produces acid in your stomach.
This enzyme produces a group of hormones called proton pumps which produce a group of hormones called proton pumps. These produce too much of a substance called acid.
This effect is necessary because your body produces your proton pumps from producing the stomach acid during your heartburn.
Take Nexium exactly as prescribed by your doctor. Do not take more or less of it or take it for longer than recommended by your doctor. You and your doctor should discuss Nexium effectiveness and safety. You and your doctor may start as low as 1 tablet per day and gradually increase the dose. You and your doctor may gradually increase the dose. You may not feel the full benefit of the higher dose of Nexium if you start taking the dose you are prescribed.
Some people may experience side effects while taking Nexium. These may include:
If you notice any other side effects while taking Nexium, call your doctor immediately or go to the Accident and Emergency department of the emergency room at the earliest.
Nexium is generally considered safe to use for people with certain conditions including heartburn. However, it is important to tell your doctor if you have taken Nexium or if you are taking any other medications including other proton pump inhibitors. They may adjust your Nexium dose, change the dose, or add additional medicines to your Nexium dose.
Yes, you can buy Nexium over the counter in your area. You can visit your doctor or local pharmacy to buy Nexium and take it as prescribed by your doctor. You can also ask your pharmacist for Nexium and take it as prescribed.
Nexium can pass into breast milk. It is recommended that you do not take Nexium while breastfeeding as it may cause birth defects in the baby.
The best Nexium dose for you depends on your condition and your risk of side effects. Taking a higher dose of Nexium can help reduce symptoms and ensure you feel full and are able to eat. Taking a lower dose of Nexium can reduce your risk of side effects including stomach pain, constipation, and difficulty sleeping.
Nexium is not recommended while breastfeeding unless prescribed by your doctor. Taking it while breastfeeding may increase the risk of complications such as breast cancer or birth defects. Nexium is not recommended for use while taking other proton pump inhibitors because it may cause harm to the developing baby.
Possible Nexium side effectsThere are no restrictions on alcohol intake while taking Nexium. You can take Nexium with or without food.
Doses of NexiumTake as prescribed by your doctor.